MediGel FAQ

How do I add medications to MediGel Sucralose?
There are two ways to add medications to Sucralose: via syringe through the top of the foil cup lid or by removing the foil lid and mixing the drug directly into the gel.

The most commonly used method is to use a syringe to deliver a medication through the foil lid.  After the medication is added, shake the cup vigorously for 10 seconds to mix the medication evenly in the gel.  Because Sucralose has a softer gel consistency, no pre-heating of the gel is required. We do, however, recommended having the gel at room temperature before mixing the medication. One trick to ensure that the medication is mixed evenly into the gel is to add a natural food color dye with the medication solution.  This enables a visual confirmation of the mixing.

After the medication is added, it is best to place the gel into a refrigerator for 30 minutes prior to using the gel with the animals.  The cooler temperature allows the gel to set and also protects the medicant during storage.

One 2oz cup will hydrate and medicate 5 mice for two days.

How do I calculate the medication dosage for using MediGel Sucralose?
To answer this question, it is best to use an example calculation. In this calculation, we are using a drug concentration of 10mg/kg/day.
For a 30 gram mouse, use 10mg/kg x 0.03kg = 0.3mg of drug/day/mouse.
A 30-35 gram mouse on average will consume 7ml of gel per day (about 0.2 ounces), so we would want a concentration of 0.30mg/7ml/gel = 0.04mg/ml.
Because our products are in 2oz containers (60ml), you would want to add 2.4mg of ibuprofen to one cup of MediGel Sucralose (60ml x 0.04mg/ml – 2.4 mg).
One cup of MediGel Sucralose medicates and hydrates 4-5 mice for 2 days.

What is the best way to store MediGel Sucralose?
Unopened MediGel can be stored at room temperature and does not require special handling. Shelf life for unopened MediGel is 24 months.

Once opened (provided the gel has not been contaminated) ClearH2O products can be stored either at room temperature or at 4°C in a sealed bag/container to prevent the product from drying out for approximately 2 weeks

Why might MediGel FBZ be different shades of blue?
The change in blue color is a result of photobleaching that occurs during the irradiation process. Because there are “hotspots” within the irradiation chamber, some of the product is subjected to a higher irradiation dose, resulting in a reduced blue color. Irradiation has no impact on drug efficacy or product stability.

How do you use MediGel FBZ?
MediGel FBZ is an efficient and cost-effective way to treat pinworm infection or to use as a prophylactic cduring quarantine. Each 4oz. cups contains 150ppm of Fenbendazole, the industry standard.

MediGel FBZ is commonly placed on the top of the cage in the water bottle slot. To use on the top of the cage, remove the water bottle and place the gel on the wire lid. The gel will not fall through the wire lid. Removing the gel is achieved by simply placing your finger between the gel and the cup. The gel will pop out easily. After the gel is removed, set the cup gently on top of the gel to prevent evaporation (MediGel is 98% water). Mice and rats will be able to reach the gel through the wire lid, getting their hydration and medication at the same time. If placing the cup on top of the cage is not an option, the gel can easily be placed on the cage floor.

One cup will hydrate and medicate 5 mice or 2 rats for 3-4 days. It is recommended that cups be replaced on a standard schedule, three times a week (Monday, Wednesday, Friday for example). This ensures that the gel remains fresh and that the animals get consistent hydration and medication.

What is the best way to store MediGel FBZ?
Unopened, MediGel FBZ is designed to be stored at room temperature and does not require special handling. The shelf life for unopened MediGel FBZ is 12 months.


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